There are connections for playstation controllers for PC. When I was in college I wired an original Playstation controller to my PC parallel port following a diagram found online. Don't even need to destroy the controller, just get a controller extention and plug into that.
Once you have the controller wired to the PC, there is a driver available for download (comes with wiring schematic, as it's hobbiest so non-standard) which will allow you to use the Playstation controller on the PC as a standard PC gamepad. It's been so long I don't remember the name, but I know there were a few of them.
If you're not into soldering stuff, I'm pretty sure someone capitalized on this and actually marketed a product like this. Search for "Playstation to PC controller" and you might find it.
Now, about controlling PTZs with it, as long as the DVR software can communicate with standard Windows game controller APIs for controll, I don't see why you couldn't hook up a DDR foot pad to your newly rigged controller extention and have windows recognize the 'keys', thus allowing you to control a PTZ with it.
-s-