Got it resolved now.
THe problem was that the varifocal cams first had to be upgraded to the latest firmware. I did this through the NVR. Before doing it, you must set the cams recordings off
Now MD settings are kept and it works.
Only thing I still have to try out is if the PTZ can be set in MD as well. AS the ptz has got no fixed view Im wondering if MD could be set for a certain pattern individually. I think this is not in the userinterface software although this should be a nice future option....